Ihe ewepụtara agwa kọfị akwụkwọ ndụ akwụkwọ ndụ
Nkọwa Ngwaahịa
Aha Ngwaahịa:Ihe ewepụtara agwa kọfị akwụkwọ ndụ akwụkwọ ndụ
Nkewa:Agwa
Akụkụ ndị dị irè: Acid Chlorogenic
Nkọwapụta ngwaahịa: 25% 50%
Nyocha:HPLC
Njikwa Ogo: N'ụlọ
Hazie: C16H18O9
Ibu molekụla:354.31
CASNo:327-97-9
Ọdịdị: Agba aja aja odontụ ntụ naisi njirimara
Nchọpụta:Na-agafe ule njirisi niile
Kedu ihe bụ agwa kọfị akwụkwọ ndụ akwụkwọ ndụ?
Agwa kọfị akwụkwọ ndụ akwụkwọ ndụ, nke a maara n'ụzọ sayensị dịka Coffea canephora robusta, bụ agwa kọfị a na-anaghị esi esi, nke pụtara na ha anaghị esi n'ọkụ.
Ikekwe uru kachasị pụta ìhè nke kọfị akwụkwọ ndụ akwụkwọ ndụ bụ mbelata ibu, ihe ewepụtara kọfị akwụkwọ ndụ akwụkwọ ndụ (GCE) bụkwa ihe mgbakwunye dị mkpa maka mbelata ibu.
A na-esi na mkpụrụ nke kọfị obere mkpụrụ osisi, kọfị ọkara mkpụrụ osisi, na osisi kọfị buru ibu nke ezinụlọ Rubiaceae wepụta ihe na-arụ ọrụ, yana chlorogenic acid dị ka ihe bụ isi na-arụ ọrụ, ma nweekwa alkaloids dị ka caffeine na fenugreek alkaloids. Chlorogenic acid bụ ihe mejupụtara phenylpropanoid nke osisi ahụ na-emepụta n'oge iku ume aerobic site na ụzọ shikimic acid, yana nje bacteria, antiviral, na-eme ka mkpụrụ ndụ ọbara ọcha dịkwuo elu, na-echebe hepatoprotective na choleretic, na-egbochi etuto ahụ, na-ebelata oke abụba, na-ewepụ ihe ndị na-emerụ ahụ ma na-akpali sistemụ akwara etiti na mmetụta ndị ọzọ. Oke caffeine kwesịrị ekwesị ga-akpali ụbụrụ ụbụrụ, na-akwalite ikpe ziri ezi, ncheta, na ọrụ mmetụta uche, ka ọrụ akwara obi na-arụ ọrụ nke ọma, na-eme ka ọbara gbasaa na mgbasa ọbara dịkwuo mma, ma melite ọrụ metabolic, caffeine nwekwara ike ibelata ike ọgwụgwụ akwara, na-akwalite mmepụta nke ihe ọṅụṅụ nri. Agbanyeghị, oke dose ma ọ bụ ojiji ogologo oge nwekwara ike imebi ahụ mmadụ, nke nwere ike ibute nkụchi obi, ma mebie imeju, afọ, akụrụ, na akụkụ ahụ dị mkpa ndị ọzọ dị n'ime. A na-ejikarị ihe e si na kọfị akwụkwọ ndụ akwụkwọ ndụ emepụta, ọkachasị n'ụlọ ọrụ ọgwụ, kemịkalụ kwa ụbọchị, na nri.
Uru ndị ọzọ nke kọfị akwụkwọ ndụ akwụkwọ ndụ:
Agbanyeghị, mmetụta dị mma nke kọfị akwụkwọ ndụ abụghị naanị ịnọgide na-ebu ibu karịa. Ọ bụghị naanị na ọ bụ ihe enyemaka dị irè ma dị mfe ịnweta, kamakwa ọ na-enyekwa uru ndị a dabere na sayensị.
Ahụike akpụkpọ ahụ - Kọfị akwụkwọ ndụ akwụkwọ ndụ nwere nnukwu ihe ndị na-agbanwe agbanwe nke na-eme ka akpụkpọ ahụ dị mma ma na-egbuke egbuke, yana ibelata ọdịdị nke wrinkles. Mgbe ejiri ya na akpụkpọ anụ anụmanụ, ọ na-egosi nnukwu antioxidant na mgbochi mbufụt.
Mbelata ọbara mgbali elu - A kwenyere na chlorogenic acid a ma ama dị na kọfị akwụkwọ ndụ akwụkwọ ndụ na-ebelata ọbara mgbali elu ma nwee ike inye ngwaọrụ dị mma maka ndị ọrịa nwere obere ọbara mgbali elu.
Nchedo mmerụ ahụ akwara - Ojiji kọfị akwụkwọ ndụ akwụkwọ ndụ na nke tozuru okè nwere ike ịrụ ọrụ n'ichebe onwe ya pụọ na mmerụ ahụ akwara mgbe emechara mmega ahụ. Na mgbakwunye, ọ nwere ike ibelata pasent nke abụba visceral, si otú a gbochie nsogbu ndị ọzọ ozugbo anụ ahụ a mepụtara homonụ na-akpata ọrịa.
Ọgụ megide ọrịa metabolic - Mgbakwunye GCE nwere mmetụta dị mma na njikwa glycemic, profaịlụ lipid, ọbara mgbali elu, na ihe ngosi iguzogide insulin na ndị ọrịa nwere ọrịa metabolic. Tinyere ihe ewepụtara na tii akwụkwọ ndụ akwụkwọ ndụ, ọ nwekwara mmetụta bara uru na imeziwanye ọrịa metabolic site na imetụta ngosipụta mkpụrụ ndụ ihe nketa metụtara ya.
Nchedo Neuroprotection - A chọpụtala na kọfị akwụkwọ ndụ akwụkwọ ndụ nwere mmetụta nchebe neuro na ọrịa Alzheimer nke insulin kpatara. Akọpụtala na ọ na-ebelata iguzogide insulin ma melite metabolism ike, nke nwere ike igbu oge mmalite ma ọ bụ igbochi ọganihu nke ọrịa Alzheimer., egosikwala na ọ nwere mmetụta bara uru na mmepe nke ọrịa Alzheimer.
Mmetụta ọgwụ:
1. Ọgwụ mgbochi ọrịa, mmetụta nke ihe ndị na-akpata ọrịa free radicals n'ahụ. Ihe e si na kọfị akwụkwọ ndụ akwụkwọ ndụ wepụta nwere ikike antioxidant siri ike n'ọtụtụ ebe, ọrụ siri ike nke na-enweghị DPPH, yana ikike mbelata iron, mana ọ bụghị ikike ion chelating metal. Ihe e si na kọfị akwụkwọ ndụ akwụkwọ ndụ wepụta nwere ọrụ antioxidant siri ike ma bụrụkwa ihe na-akpata ọrịa sitere n'okike.
2. Ọgwụ nje na-egbu nje. Acid chlorogenic nwere nje na-egbu nje na hemostatic, na-eme ka mkpụrụ ndụ ọbara ọcha dịkwuo elu, na-ebelata oge ọbara na-agba, yana mmetụta ndị ọzọ. Acid chlorogenic nwere mmetụta mgbochi na igbu egbu dị ukwuu na ọtụtụ nje bacteria na-akpata ọrịa, dịka Staphylococcus aureus, hemolytic streptococcus, dysentery cocci, typhoid bacillus, pneumococcus, wdg. Acid chlorogenic nwere mmetụta doro anya na mbufụt akpịrị na ọrịa akpụkpọ ahụ ma ejiri ya agwọ ọrịa nje bacteria na-efe efe nke ukwuu.
3. Ọgwụ mgbochi mgbanwe, mmetụta mgbochi etuto ahụ. Acid chlorogenic nwere ikike mgbanwe siri ike, nwere ike igbochi mgbanwe nke aflatoxin B kpatara na mgbanwe nke mmeghachi omume nke sub-digestion na-akpata, ma nwee ike ibelata mgbanwe erythrocyte ọkpụkpụ nke γ-ray kpatara; chlorogenic acid nwere ike ibelata ojiji nke carcinogens na njem ya n'ime imeju iji nweta mmetụta nke mgbochi kansa, mgbochi kansa. Acid chlorogenic nwere mmetụta dị ukwuu na-egbochi kansa eriri afọ, kansa imeju, na kansa laryngeal, a na-ewerekwa ya dị ka ihe nchebe chemo dị irè megide kansa.
4. Nchedo obi na akwara obi. A nwaleela Chlorogenic acid dị ka ihe na-eme ka mkpụrụ ndụ dị ndụ na ihe na-egbochi ọrịa kansa iji gosi na ọrụ chlorogenic acid a nwere ike inwe mmetụta nchebe na sistemụ obi. Site na iwepụ radicals free na anti-lipid peroxidation, chlorogenic acid nwere ike ichebe mkpụrụ ndụ endothelial vascular, nke nwere ike ịrụ ọrụ na mgbochi atherosclerosis, ọrịa thromboembolic, na ọbara mgbali elu.
5. Mmetụta ndị ọzọ Chlorogenic acid na ihe ndị sitere na ya egosila ụfọdụ mmetụta mgbochi na ọmụmụ ihe mgbochi HIV, chlorogenic acid nwekwara mmetụta mgbochi pụrụ iche na HAase na glucose xun-monophosphatase, ma nwee mmetụta ụfọdụ na ọgwụgwọ ọnya, mmiri mmiri akpụkpọ ahụ, mmanụ nkwonkwo, na mgbochi mbufụt. Ntinye chlorogenic acid n'ọnụ nwere ike ịkpalite mwepụ nke bile nke ukwuu, yana mmetụta cholorogenic; chlorogenic acid nwekwara mmetụta mgbochi dị ukwuu na ọnya afọ, ọ nwekwara ike igbochi erythrocyte hemolysis nke H202 kpatara na oke.
Asambodo Nyocha
| Aha ngwaahịa | Ihe ewepụtara agwa kọfị akwụkwọ ndụ akwụkwọ ndụ | Isi Iyi Osisi | Kọfị L |
| Ogbe NO. | RW-GCB20210508 | Ọnụọgụ otu | 1000 kgs |
| Ụbọchị Mmepụta | Mee. 08. 2021 | Ụbọchị Nnyocha | Mee. 17. 2021 |
| Ihe fọdụrụnụ | Mmiri na Ethanol | Akụkụ ejiri | Agwa |
| IHE | Nkọwapụta | ỤZỌ | Nsonaazụ ule |
| Data Anụ ahụ na Kemikal | |||
| Agba | Ntụ ntụ odo aja aja | Organoleptic | Ndị ruru eru |
| Ordour | Njirimara | Organoleptic | Ndị ruru eru |
| Ọdịdị | Ntụ ntụ dị mma | Organoleptic | Ndị ruru eru |
| Ogo Nyocha | |||
| Nchọpụta | Yiri ihe nlele RS | HPTLC | Otu |
| Acid Chlorogenic | ≥50.0% | HPLC | 51.63% |
| Mfu mgbe a kpọrọ nkụ | 5.0% Kachasị. | Eur.Ph.7.0 [2.5.12] | 3.21% |
| Ntụ zuru oke | 5.0% Kachasị. | Eur.Ph.7.0 [2.4.16] | 3.62% |
| Sievu | 100% ngafe 80 ntupu | USP36<786> | Kwekọrịta |
| Njupụta dị nro | 20~60 g/100ml | Eur.Ph.7.0 [2.9.34] | 53.38 g/100ml |
| Njupụta Mpịakọta | 30~80 g/100ml | Eur.Ph.7.0 [2.9.34] | 72.38 g/100ml |
| Ihe fọdụrụnụ | Zute Eur.Ph.7.0 <5.4> | Eur.Ph.7.0 <2.4.24> | Ndị ruru eru |
| Ihe fọdụrụ n'ọgwụ nje | Mezue ihe USP chọrọ | USP36 <561> | Ndị ruru eru |
| Ọla dị arọ | |||
| Mkpokọta Ọla Dị Oké Ọnụ Ahịa | Oke kachasị: 10ppm | Eur.Ph.7.0 <2.2.58> ICP-MS | 1.388g/kg |
| Lead (Pb) | Oke kachasị: 3.0ppm. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.062g/kg |
| Arsenic (Dịka) | Oke kachasị: 2.0ppm. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.005g/kg |
| Cadmium (Cd) | Oke kachasị: 1.0ppm | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.005g/kg |
| Mercury (Hg) | Oke kachasị: 0.5ppm | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.025g/kg |
| Nnwale Microbe | |||
| Mkpokọta Ọnụọgụ Efere | NMT 1000cfu/g | USP <2021> | Ndị ruru eru |
| Yist na Ebu zuru oke | NMT 100cfu/g | USP <2021> | Ndị ruru eru |
| E.Coli | Ihe na-adịghị mma | USP <2021> | Ihe na-adịghị mma |
| Salmonella | Ihe na-adịghị mma | USP <2021> | Ihe na-adịghị mma |
| Nkwakọba na Nchekwa | A na-etinye ya n'ime drum akwụkwọ na akpa plastik abụọ dị n'ime. | ||
| NW: 25kg | |||
| Debe n'ime akpa mechiri emechi nke ọma, ebe mmiri, ìhè, na ikuku oxygen na-agaghị eru. | |||
| Ndụ nchekwa | Ọnwa iri abụọ na anọ n'okpuru ọnọdụ dị n'elu na n'ime ngwugwu mbụ ya. | ||
Onye nyocha: Dang Wang
Onye lere ya anya: Lei Li
Onye kwadoro ya bụ: Yang Zhang
Ị chọrọ ịbịa ileta ụlọ ọrụ mmepụta ihe anyị?
Ị na-eche banyere asambodo anyị nwere?
Ọrụ Ngwaahịa
Agwa Kọfị Akwụkwọ Ndụ maka mbelata ibu na-ebelata ikuku oxygen n'efu, na-ebelata abụba ọbara, na-echebe akụrụ, na-ebelata ibu ibu, ihe mgbakwunye nri, mmetụta dị mkpa nke mgbochi ọbara mgbali elu, na mmetụta ndị na-adịghị egbu egbu ma dị nro; Mgbochi na ọgwụgwọ dị egwu nke ọrịa kansa nasopharyngeal, nwere mmetụta ọgwụgwọ tumor dị egwu, ma nwee obere nsí na njirimara nchekwa; Chebe akụrụ ma melite ọrụ ahụ ji alụso ọrịa ọgụ; Na-eguzogide oxidation, ịka nká, na iguzogide ịka nká ọkpụkpụ; Ọgwụ nje bacteria, antiviral, diuresis, cholagogue, na-ebelata abụba ọbara, ma gbochie ime ọpụpụ; na-ekpochapụ okpomọkụ na iwepụ ihe na-egbu egbu, na-eme ka akpụkpọ ahụ dị mmiri mmiri ma na-eme ka ọdịdị ya ka mma, na-ebelata oke mmanya na ụtaba.
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