Mmalite nke Citrus Aurantium

Citrus aurantium, osisi nke ezinụlọ rutaceae, na-ekesa na China. Citrus aurantium bụ aha ọdịnala ndị China maka lime. Na nkà mmụta ọgwụ ndị China, citrus aurantium bụ ahịhịa ọdịnala nke a na-ejikarị amụba agụụ na ịhazi qi (ike). N'Itali, citrus aurantium abụrụla ọgwụgwọ ọdịnala kemgbe narị afọ nke 16, nke a na-eji agwọ ahụ ọkụ dị ka ịba yana ọgwụ mgbochi nje. Nnyocha e mere n'oge na-adịbeghị anya gosiri na citrus aurantium nwere ike dochie ephedra na ọgwụgwọ oke ibu na-enweghị mmetụta ọjọọ nke obi.

Ihe mejupụtara nke citrus aurantium bụ hesperidin, neohesperidin, nobiletin, auranetin, aurantiamarin, nuringin, synephrine, limonin.

Ihe na-arụ ọrụ

Auranetin, neohesperidin, neohesperidin, nobiletin, D-limonene, auranetin, aurantiamarin, citrin, synephrine, limonin.

Ihe onwunwe

Crystallization, ebe mgbaze 184-1850C, kristal carbonate 151-152, na-agbaze ngwa ngwa na mmiri. Bitartrate, ebe mgbaze 188-189, soluble na mmiri, siri ike igbari na ethanol, ọ fọrọ nke nta ka ọ bụrụ ihe na-adịghị ike na chloroform, ether. Hydrochloride, crystal enweghị agba (ethanol-ethyl ether), ebe agbaze 166-167. Mgbasa agbụrụ dị mfe ime na chromatography nkewa nke acid siri ike na resins mgbanwe ion base.

Mmetụta ọgwụ
1. Mmetụta na akpanwa: Fructus Aurantii na Fructus Aurantii Fructus Decoction si atọ dị iche iche na-emepụta ebe (Sichuan, Jiangxi, na Hunan) gosiri mmetụta inhibitory na akpanwa in vitro nke ụmụ oke (dị ime na ndị na-adịghị ime); Akpa oke bekee nwere obi ụtọ ma na vivo na in vitro (dị ime na ọ bụghị ime). Fistula uterine oke bekee gosikwara na ọ na-eme ka mgbochi nke akpanwa sie ike, na-abawanye ụba, na ọbụna mkpụkọ tetanic. Fructus Aurantii tincture na Fructus Aurantii mmiri wepụ nwekwara ike ịkpali akpanwa oke bekee (na vivo na in vitro). A gbochiri akpanwa òké (in vitro). Ihe alkaloid dịpụrụ adịpụ na Fructus Aurantii na oroma Lycium nwekwara mmetụta nkwekọrịta ụfọdụ na akpanwa oke bekee na vitro, karịsịa na akwara uterine nke pituitrin nwere mmasị na ya. Akụkụ nke alkaloid wepụrụ nwere mmetụta ntụrụndụ na akpanwa oke bekee na vitro, na mmetụta ntụrụndụ nke akpanwa pụtara ìhè mgbe mkpali hypophysial gasịrị. Cirantin, nke dịpụrụ adịpụ na Fructus Aurantii Fructus Peel, na-egbochi ọrụ hyaluronate gburugburu ovary, nke nwere ike jikọta ya na mmetụta mgbochi ya (na-egbochi fatịlaịza).

2. Mmetụta na eriri afọ: Fructus Aurantii na Fructus Aurantii sitere na ebe obibi atọ dị iche iche gbochiri eriri afọ na oke na oke bekee; A gbochiri ọtụtụ tubes eriri afọ na oke bekee, mana ole na ole enweghị mgbanwe ọ bụla. Fructus Aurantii na mwepu mmiri ya gbochiri tubes eriri afọ ụmụ oke (in vitro) na oke bekee (in vitro). Nnukwu ntinye uche (1: 1000) gbochiri obere eriri afọ nke oke bekee na ezi pigs ma gbochie mmetụta nke acetylcholine na histamine. Ntinye uche dị ala (1: 10 000), mgbe obere oge nke mgbochi gasịrị, nwere ike igosi mmetụta na-akpali akpali, njupụta na-abawanye, na ugboro ugboro na-emewanyewanye. N'ime nkịta ndị na-egbu egbu, a na-egbochi ọnụnọ nke eriri afọ n'ụzọ doro anya site na decoctions. Ma maka nkịta nwere gastroenterostomy, ọ nwere mmetụta na-akpali akpali, nke nwere ike ime ka mgbatị eriri afọ na nkwụsị nke mgbagwoju anya dị ike.

3. Mmetụta na obi na arịa ọbara: obere ego nke excitability na nnukwu ihe mgbochi na obi nke toad in vitro. Fructus Aurantii na Fructus Aurantii Aurantii aqueous decoction, Fructus Aurantii tincture, na mmiri wepụ bụ otu ihe ahụ. Fructus Aurantii decoction ma ọ bụ mmanya na-egbu egbu nke a na-agbanye n'ime eriri afọ nwere ike ime ka nkwalite nrụgide dị ukwuu. Fructus Aurantii na Fructus Aurantii Fructus sitere na ebe obibi atọ dị iche iche egosipụtara na ha nwere mmetụta vasoconstriction dị nro site n'ọbara akwara akwara nke toads. N'ime nkịta aneshetized, enwere mmetụta ọbara mgbali elu na ngwa ngwa. Enweghị ịda mbà n'obi iku ume ma ọ bụ hypotension nke epinephrine kpatara, ọ dịghịkwa mmụba doro anya na ọnụọgụ obi.

Usoro na-akwalite nrụgide na-emetụta ihe ndị a:

3.1. Ihe na-akpali akpali nke ndị na-anabata α, na-eme ka vasoconstriction na akụkụ ụfọdụ (phenylzoline nwere ike gbanwee nkwalite nrụgide n'ime mmeghachi omume antihypertensive).

3.2. Mgbagwoju anya myocardial na-abawanye na mmepụta obi na-abawanye (mkpọsa mkpụrụ obi nke Guinea pig dịpụrụ adịpụ na nkwadebe obi obi). Mgbe reserpine gasịrị, mmetụta na-akwalite nrụgide nke Fructus aurantii aurantii dị ịrịba ama karị. Ọ na-abawanye ụba nke akwara obi (289.4% mmụba nke akwara akwara site na bubble flowmeter) yana mmụba ụbụrụ na ọbara akụrụ site na 86.4% na 64.5% na nkezi, bụ nke dị nnọọ iche na norepinephrine. Enwere mbelata nke nrịba ọbara femoral na mmụba dị ntakịrị mana ọ dị obere na oriri oxygen myocardial, nke na-adakọghị na mmụba dị ukwuu na mgbaba akwara. N'ime ule ECG na nkịta na ezi pigs, arrhythmia (ventricular tachycardia ma ọ bụ ngọngọ atrioventricular) nke nnukwu aurantii aurantii kpatara adịghị njọ. Dabere na njirimara ndị a dị n'elu, a na-atụ aro ka a gwọọ ujo cardiogenic. Alkaloids dịpụrụ adịpụ na Fructus Aurantii na oroma Lycium nwekwara ike ime ka esemokwu nke akwara dị nro dịkwuo mma nwa oge, ọkachasị mgbe ejiri pituitrin na-agwọ ya.

4. Antithrombotic: Nnwale in vitro nke 0.1g/ml Fructus Aurantii aqua decoction gosipụtara mmetụta antithrombotic doro anya.

5. Mmeghachi omume nfụkasị ahụ: 100mg / kg static pulse injection of Fructus Aurantii Aurantii mmiri wepụ nwere ike igbochi mmeghachi ahụ nfụkasị anụ ahụ (PCA) na oke, na 50μg / ml nwere ike igbochi nkwụsị nke histamine site na sel mast abdominal oke.

6. Mmetụta ndị ọzọ: Citrus osisi mycin nwere ike ibelata ọdịnaya nke cholestatin na serum na imeju nke oke nke nri nwere cholesterol na-eri nri. Mmanya mmanya nke Fructus Aurantii nwere mmetụta mgbochi na mycobacterium ụkwara nta H37Rv in vitro, na ntinye ihe mgbochi ya bụ 1:1000. Decoction mmiri ya enweghị mmetụta na bronchus ezi ezi. A kọwapụtara na ihe ọṅụṅụ mkpụrụ osisi citrus na-eme ka ọ̀tụ̀tụ̀ iko achịcha na-agbari agbagọ ma ghara ibelata ọrụ ya mgbe esichara, n'ihi ya, ọ bụghị akụkụ enzymatic. Isi ihe eji eji ihe ọṅụṅụ oroma eme ọgwụ bụ na ọ bara ụba na vitamin C ma nwee nnukwu vitamin A na B. Peel enweghị vitamin C kama ọ bara ụba na vitamin A. Ọ na-atọ ụtọ ilu ma na-ewusi afọ ike. Ụmụaka dị ka ịweta ọnụ ọgụgụ buru ibu nke peels nwere ike ịkpata nsị (mgbu afọ, mgbu).

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MakaCitrus aurantium wepụ, biko kpọtụrụ anyị. Anyị na-eche gị ebe a mgbe ọ bụla!!!