Akpụkpọ anụ na mkpụrụ nke mkpụrụ vaịn na tomato nwere resveratrol, na-eme ka mmanya na-acha uhie uhie bara ụba na ogige a. Nnyocha na-egosi na ọ nwere nnukwu uru ahụike, mana ị ga-achọ ịmatakwu gbasara ego mgbakwunye ị ga-ewere.
Ọ bụrụ na ị nụla na mmanya na-acha ọbara ọbara na-enyere aka belata cholesterol, mgbe ahụ ị nwere ike nụ maka resveratrol, ihe ọkụkụ nke a na-atụgharị na mmanya uhie.
Ma na mgbakwunye na ịbụ akụkụ bara uru nke mmanya uhie na nri ndị ọzọ, resveratrol nwekwara ikike ahụike.
N'ezie, ihe mgbakwunye resveratrol jikọtara ya na ọtụtụ uru ahụike dị ịtụnanya, gụnyere ichebe ọrụ ụbụrụ na ibelata ọbara mgbali (1, 2, 3, 4).
Edemede a na-akọwa ihe ịchọrọ ịma gbasara resveratrol, gụnyere uru ahụike asaa kachasị elu.
Resveratrol bụ osisi na-arụ ọrụ dị ka antioxidant. Isi nri nri gụnyere mmanya na-acha ọbara ọbara, mkpụrụ vaịn, ụfọdụ beri, na ahụekere (5, 6).
Ngwakọta a na-etinyekarị uche na skins na mkpụrụ nke mkpụrụ vaịn na tomato. Akụkụ ndị a nke mkpụrụ vaịn na-etinye aka na ịgba ụka nke mmanya na-acha ọbara ọbara, ya mere enwere nnukwu ịta resveratrol (5, 7).
Otú ọ dị, a na-eme ọtụtụ nchọpụta resveratrol na ụmụ anụmanụ na n'ime tubes ule na-eji nnukwu onyinye a (5, 8).
N'ime obere ọmụmụ ihe na ụmụ mmadụ, ihe ka ọtụtụ lekwasịrị anya n'ụdị agbakwunyere, nke a na-ahụ na mkpokọta dị elu karịa nke enwetara site na nri (5).
Resveratrol bụ ihe antioxidant dị na mmanya uhie, beri na ahụekere. Ọtụtụ ọmụmụ mmadụ ejirila ihe mgbakwunye nwere ọkwa resveratrol dị elu.
N'ihi njirimara antioxidant ya, resveratrol nwere ike ịbụ mgbakwunye na-ekwe nkwa maka ibelata ọbara mgbali elu (9).
Nyocha 2015 kwubiri na oke doses nwere ike inye aka belata nrụgide na mgbidi akwara mgbe obi na-akụ (3).
A na-akpọ nrụgide systolic ọbara mgbali ma na-apụta dị ka ọnụọgụ dị elu na ọgụgụ ọbara mgbali.
Ọbara mgbali elu systolic na-abawanye na afọ n'ihi atherosclerosis. Mgbe ọ dị elu, ọ bụ ihe ize ndụ maka ọrịa obi.
Resveratrol nwere ike nweta mmetụta na-ebelata ọbara mgbali site n'inyere aka ịmepụta nitric oxide ọzọ, nke na-eme ka arịa ọbara kwụsịlata (10, 11).
Otú ọ dị, ndị na-amụ akwụkwọ kwuru na ọ dị mkpa ka a na-eme nchọpụta ndị ọzọ iji mee ka a na-atụ aro ka ọ bụrụ ihe kachasị mma nke resveratrol maka mmetụta kachasị na ọbara mgbali elu.
Ọtụtụ ọmụmụ anụmanụ egosila na mgbakwunye resveratrol nwere ike gbanwee lipids ọbara n'ụzọ ahụike (12, 13).
N'ime ọmụmụ 2016, a na-enye ụmụ oke nri dị elu na protein na abụba polyunsaturated nke ejiri resveratrol gbakwunyere.
Ndị nyocha ahụ chọpụtara na nkezi mkpokọta cholesterol na ịdị arọ nke ụmụ oke ahụ belatara, ebe ọkwa “ezigbo” HDL cholesterol mụbara (13).
Resveratrol yiri ka ọ na-emetụta ọkwa cholesterol site na ibelata ọrụ enzymes na-achịkwa mmepụta cholesterol (13).
Dị ka antioxidant, ọ na-ebelata oxidation nke "ọjọọ" LDL cholesterol. Oxidation nke LDL na-eduga n'ichepụta plaque na mgbidi akwara (9, 14).
Mgbe ọnwa isii nke ọgwụgwọ gasịrị, ndị sonyere na-ewere mwepu mkpụrụ vaịn na-enweghị uche ma ọ bụ placebo nwere mbelata 4.5% na LDL na mbelata 20% na LDL oxidized (15).
Ihe mgbakwunye resveratrol nwere ike imezi ọkwa lipid ọbara na anụmanụ. N'ịbụ ndị antioxidant, ha na-ebelata oxidation nke LDL cholesterol.
Ikike nke ogige ahụ ịgbatị ndụ nke ihe dị iche iche dị iche iche aghọwo akụkụ bụ isi nke nyocha (16).
Enwere ihe akaebe na resveratrol na-arụ ọrụ ụfọdụ mkpụrụ ndụ ihe nketa, si otú a na-egbochi ọrịa nke ịka nká (17).
Nke a na-arụ ọrụ n'otu ụzọ ahụ na mmachi calorie, nke gosipụtara nsonaazụ na-ekwe nkwa na-abawanye ndụ site n'ịgbanwe ụzọ e si egosipụta mkpụrụ ndụ ihe nketa (18, 19).
Nlebanya nke ọmụmụ na-enyocha njikọ a chọpụtara na resveratrol gbatịrị ogologo ndụ na 60% nke ihe ndị a na-amụ, mana mmetụta ahụ kacha pụta ìhè n'ime ihe ndị na-abụghị ihe jikọrọ ya na ụmụ mmadụ, dị ka ikpuru na azụ (20).
Ọmụmụ anụmanụ egosila na mgbakwunye resveratrol nwere ike ịgbatị ndụ. Agbanyeghị, amabeghị ma ha ga-enwe mmetụta yiri nke ahụ n'ime mmadụ.
Ọtụtụ nchọpụta egosila na ịṅụ mmanya na-acha uhie uhie nwere ike inye aka belata ọgụgụ isi metụtara afọ (21, 22, 23, 24).
Ọ dị ka ọ na-egbochi irighiri protein a na-akpọ amyloid beta, bụ nke dị oke mkpa n'ịmepụta akara ngosi nke ọrịa Alzheimer (21, 25).
Ọ bụ ezie na nchọpụta a na-adọrọ mmasị, ndị ọkà mmụta sayensị ka nwere ajụjụ gbasara ikike anụ ahụ nwere iji resveratrol na-eme ihe, na-egbochi iji ya ozugbo dị ka ihe mgbakwunye nchebe ụbụrụ (1, 2).
Resveratrol bụ ọgwụ antioxidant siri ike na mgbochi mkpali nke nwere ike ichebe mkpụrụ ndụ ụbụrụ site na mmebi.
Uru ndị a gụnyere imeziwanye mmetụta insulin na igbochi nsogbu ọrịa shuga (26,27,28,29).
Otu nkọwa maka otú resveratrol si arụ ọrụ bụ na ọ nwere ike igbochi enzyme ime ka glucose ghọọ sorbitol, mmanya na-egbu egbu.
Mgbe oke sorbitol na-akwakọba n'ime ahụ ndị nwere ọrịa shuga, ọ nwere ike ịkpata nrụgide oxidative na-emebi cell (30, 31).
Resveratrol nwere ike ịbara ndị ọrịa shuga uru karịa ndị na-abụghị ndị ọrịa mamịrị. N'ime otu ọmụmụ anụmanụ, a chọpụtara na mmanya na-acha ọbara ọbara na resveratrol bụ antioxidants dị ike karịa ụmụ oke na-arịa ọrịa shuga karịa ụmụ oke na-enweghị ọrịa shuga (32).
Ndị na-eme nchọpụta na-ekwu na enwere ike iji ogige ahụ na-agwọ ọrịa shuga na nsogbu ya n'ọdịnihu, mana ọ dị mkpa nyocha ọzọ.
Resveratrol na-enyere ụmụ oke aka imeziwanye mmetụta insulin na ọgụ nsogbu ọrịa shuga. N'ọdịnihu, ndị ọrịa nwere ọrịa shuga nwekwara ike irite uru na ọgwụgwọ resveratrol.
A na-amụ ihe mgbakwunye ahịhịa dị ka ụzọ isi gwọọ ma gbochie mgbu nkwonkwo. Mgbe ewere ya dị ka mgbakwunye, resveratrol nwere ike inye aka chebe cartilage site na ndakpọ (33, 34).
Otu nnyocha gbabara resveratrol n'ime nkwonkwo ikpere nke oke bekee arthritic wee chọpụta na oke bekee ndị a nwere obere mmebi nke cartilage (34).
Ndị ọzọ nyocha-tube na ọmụmụ anụmanụ egosila ikike nke a nwere ike belata mbufụt ma gbochie mmebi nkwonkwo (33, 35, 36, 37).
A mụọla Resveratrol maka ike ya igbochi na ịgwọ ọrịa kansa, karịsịa na tubes ule. Agbanyeghị, agwakọtala nsonaazụ (30, 38, 39).
E gosiputara ịlụ ọgụ dị iche iche nke mkpụrụ ndụ kansa na anụmanụ na nyocha tube, gụnyere afọ, eriri afọ, akpụkpọ anụ, ara na ọrịa prostate (40, 41, 42, 43, 44).
Otú ọ dị, ebe ọ bụ na a na-eduzi ọmụmụ ihe ruo ugbu a na tubes ule na ụmụ anụmanụ, a na-achọkwu nyocha iji ghọta ma ọ bụrụ na enwere ike iji onyinye a na-agwọ ọrịa cancer na ụmụ mmadụ.
Ọmụmụ ihe na-eji ihe mgbakwunye resveratrol achọpụtala enweghị nnukwu ihe egwu. Ọ dị ka ndị ahụ ike na-anabata ha nke ọma (47).
Otú ọ dị, ekwesịrị iburu n'uche na ugbu a enweghi ndụmọdụ gbasara ego ole resveratrol kwesịrị iji nweta uru ahụike.
Enwekwara ụfọdụ ịdọ aka ná ntị, karịsịa gbasara otu resveratrol si emekọrịta na ọgwụ ndị ọzọ.
N'ihi na egosila nnukwu doses iji gbochie mkpụkọ ọbara na tubes ule, ha nwere ike ịbawanye ọbara ọgbụgba ma ọ bụ ọnya mgbe ejiri ọgwụ mgbochi dị ka heparin ma ọ bụ warfarin, ma ọ bụ ụfọdụ ọgwụ mgbu (48, 49).
Resveratrol na-egbochikwa enzymes nke na-enyere aka wepụ ụfọdụ ogige n'ime ahụ. Nke a pụtara na ụfọdụ ọgwụ nwere ike iru ọkwa adịghị mma. Ndị a na-agụnye ụfọdụ ọgwụ na-ebelata ọbara mgbali elu, ọgwụ mgbochi nchegbu, na immunosuppressants (50).
Ọ bụrụ na ị na-aṅụ ọgwụ ugbu a, ị nwere ike ịchọrọ dọkịta gị tupu ị were resveratrol.