Ellagic acid bụ ihe sitere n'okike nke a na-ahụkarị na mkpụrụ pọmigranet. Ọ bụghị ihe ijuanya na ellagic acid aghọọla ihe a na-ahụkarị dịka ihe mgbakwunye nri n'afọ ndị na-adịbeghị anya.

IheỤlọ ọrụ mmepụta ihe ọṅụṅụ mkpụrụ pọmigranet nke China bụ Ellagic AcidAghọọla otu n'ime isi ihe ndị na-emepụta ellagic acid n'ụwa niile, na-emepụta ihe mgbakwunye dị elu nke na-aghọ ihe ngwọta ngwa ngwa maka ndị chọrọ ịnọgide na-enwe ahụike kacha mma n'ụzọ ebumpụta ụwa. Rivo bụ nhọrọ magburu onwe ya iji nye mkpụrụ pọmigranet ellagic acid.

Ellagic acid nwere ọtụtụ ọrụ bioactive, ebe a anyị na-enyocha uru nke ellagic acid na ihe kpatara osisi pomegranate ellagic acid nke China ji bụrụ ihe a na-ahụkarị n'etiti ndị na-ahụ maka ahụike.

Njirimara antioxidant nke ellagic acid

1. Ịlụso oke radicals ọgụ

Kemgbe afọ 1950, a na-enyocha ma na-eme nnyocha banyere ihe ndị na-egbochi ọrịa nke ellagic acid na vivo na in vitro, ọtụtụ ihe ndị e mere na-egosikwa na ellagic acid nwere ike iwepụ ihe ndị na-akpata ọrịa na igbochi ọrịa. Ellagic acid nwere mmetụta dị ukwuu n'ahụ oxygen radicals na hydroxyl radicals, ikike ya nke iwepụ ihe ndị na-akpata ọrịa na-akpata ọrịa na-ebelatakwa ihe ndị ....

2. Na-egbochi lipid peroxidation

Maka mgbochi lipid peroxidation, a na-ewere ellagic acid dị ka ihe kacha mma na-egbochi mmalite lipid peroxidation dabere na microsomal NADPH, ellagic acid nwekwara ike igbochi lipid peroxidation nke adriamycin kpatara nke ukwuu. Ellagic acid na-egbochi iron myoglobin/hydrogen peroxide-dependent lipid peroxidation. Ellagic acid na-egbochi lipid peroxidation (LPO) nke ihe ndị dị n'èzí na-akpata na mkpụrụ ndụ T, na-egbochi mmepụta oxygen species (ros) na-emegharị ma na-eme ka ọnwụ mkpụrụ ndụ nke cytotoxins kpatara belata.

3. Ọrụ antioxidant ndị ọzọ

Asịd Ellagic nwere ike ibelata mmebi mkpụrụ ndụ nke radieshon, hydrogen peroxide na mitomycin C kpatara na mkpụrụ ndụ ụmị ọkpụkpụ òké. Asịd Ellagic gbochiri oxidation nke DCDHF nke peroxynitrite kpatara yana oxidation nke peroxynitrite n'onwe ya. N'otu oge ahụ, ellagic acid gbochiri mgbawa otu eriri nke peroxynitrite kpatara nke pTZ 18U plasmid DNA na nitration nke otu tyrosinyl na protein calf serum. Ya mere, na vitro, ellagic acid na-echebe biomolecules site na mmebi oxidative na nitrosative nke nitrite kpatara.

Ihe ndị ọzọ nke ellagic acid

Mmegharị nke astrocytes nke pancreas bụ ihe dị mkpa na-akpata ọnọdụ dịka pancreatic fibrosis na pancreatitis acute. Ellagic acid na-egbochi interleukin 1b (IL-1) na tumor necrosis factor-α (TNF-α)-induced activator protein-1 na mitogen-activated protein kinase, si otú a na-egbochi ntụgharị nke ọhụrụ pancreatic astrocytes ka ọ bụrụ phenotype fibrillogenic activated. Ellagic acid na-arụ ọrụ dị ka metabolite nke abụọ megide ọrụ eosinophil na ụdị β-glucan peritonitis. Ellagic acid bụ ihe na-egbochi eosinophils nke ọma ma enwere ike iji ya gwọọ mbufụt nfụkasị ahụ. Ellagic acid nwere mmetụta nchebe hepatoprotective ebe ọ na-eguzogide hepatotoxicity nke carbon tetrachloride kpatara na vivo na in vitro, ma na-eguzogidekwa lipid peroxidation nke tert-butyl hydroperoxide kpatara.

A na-ahụ mkpụrụ ndụ melanocytes n'ime akwa basal nke epidermis, ebe a na-emepụta melanin. Ihe e ji emepụta melanin bụ tyrosine, nke tyrosinase ga-agbanwe n'usoro ka ọ bụrụ dopa, dopaquinone na melanin n'ikpeazụ. Ellagic acid na-egbochi mmepụta melanin site n'igbochi ọrụ nke tyrosinase.

Ya mere, a na-ejikarị ellagic acid dị ọcha dị ka ihe mgbakwunye na ọgwụ, nri ahụike na ihe ịchọ mma dị ka ihe na-arụ ọrụ maka antioxidant, mgbochi nje megide adịghị ike mmadụ, ịcha akpụkpọ ahụ, wdg.

Gịnị mere ị ga-eji họrọỤlọ ọrụ mmepụta ihe ọṅụṅụ mkpụrụ pọmigranet nke China bụ Ellagic Acid?

Ụlọ ọrụ mmepụta ihe nke pomegranate Ellagic Acid nke China na-aghọ onye na-eweta ngwaahịa kachasị mma n'ụwa, n'ihi ngwaọrụ na ụzọ mmepụta ya dị mma. Ha emeela nke ọma n'ịmepụta ihe mgbakwunye dị elu, na-ahụ na ngwaahịa ha na-emezu ụkpụrụ nchekwa zuru ụwa ọnụ. N'ihi ya, ihe mgbakwunye ellagic acid ha na-enye uru zuru oke dịka ikike mgbochi mbufụt na mgbochi etuto ahụ.

Na mmechi, Ellagic acid nwere nnukwu uru yana ịdabere na mgbakwunye dị mma, dị elu dịka ndị nke sitere na ya mepụtaraỤlọ ọrụ mmepụta ihe ọṅụṅụ mkpụrụ pọmigranet nke China bụ Ellagic Acidbụ ụzọ kachasị mma isi nweta ọgwụ dị mma ma dị mma nke na-abara ahụike gị uru n'enweghị mgbagha. Ya mere, ọ bụrụ na ịchọrọ ijikwa ahụike ndị mmadụ ma nọgide na-ebi ndụ dị mma, tụlee itinye mgbakwunye ellagic acid na ngwaahịa gị taa.

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